Many men face the unwelcome realities of aging, such as thinning hair, decreased energy, and a diminished sex drive. For these individuals, the natural decline in testosterone levels, often referred to as Andropause or colloquially as “Manopause,” can significantly impact their quality of life. The telehealth startup Ulo aims to address these issues by providing Testosterone Replacement Therapy (TRT) directly to men’s homes.
Interest in TRT has surged as endocrinologists highlight the symptoms associated with low testosterone. This decline typically begins in men’s late 30s or 40s and can result in fatigue, hair loss, and reduced muscle mass. According to Deep Patel, co-founder of Ulo, “Men are tired of feeling off and being told it’s just aging or stress.” He emphasizes that many men are realizing that feeling constantly exhausted or unmotivated is not a normal part of aging.
Doctors often recommend blood tests for men exhibiting symptoms of low testosterone. Normal testosterone levels range from 300 to 1,000 nanograms per deciliter. Shockingly, nearly 39% of men aged 45 and older are affected by low testosterone, a condition medically known as hypogonadism. Patel believes that the problem is more widespread than commonly understood, affecting men in their 20s, 30s, and 40s as well, often due to stress, poor diet, and lack of sleep.
Ulo launched initially focusing on men’s health issues such as hair loss, but gradually expanded into the TRT sector, inspired by the observable benefits this treatment provided to those around them. “I watched friends lose their hair way too young and struggle in silence,” Patel recalls. He recognized that many were also suffering from low testosterone, impacting their energy and motivation despite efforts to improve their diet and sleep.
A 2023 study published in the Journal of Clinical Endocrinology revealed that testosterone levels in American men have declined approximately 1% annually since the 1980s, a trend Patel describes as a “silent epidemic.” Emerging research indicates that TRT may be one of the most effective treatments for men with low levels. A survey from 2019 found that 52% of men reported increased energy levels after starting testosterone therapy, while 42% noticed improvements in libido, and 29% experienced muscle growth.
Ulo streamlines access to TRT through a simple process. First, men take a blood test and consult with a licensed physician. The physician assesses the lab results, symptoms, and medical history before prescribing a tailored treatment plan. While injections are the most common method of delivery, Ulo also provides alternatives such as gels and creams for those who prefer them. Once the plan is established, the treatment is delivered directly to the patient’s home.
Patel notes that most men begin to notice changes within a few weeks, including heightened energy, mental clarity, and improved libido. After two to three months, many also see changes in body composition, with increased muscle mass and a reduction in stubborn fat. Alongside these physical transformations, participants often report a boost in confidence.
While TRT can yield significant benefits, it is not without risks. Common side effects include acne, water retention, and elevated red blood cell counts. Some men may experience testicular shrinkage or reduced fertility, and cardiovascular risks exist for certain individuals. Currently, TRT is only FDA-approved for specific medical conditions, such as hypogonadism. Earlier this year, the FDA issued changes to labeling for testosterone products, highlighting potential side effects like increased blood pressure.
Patel emphasizes the importance of medical guidance when considering TRT, warning against the dangers of unregulated medications obtained online. Ulo’s approach prioritizes thorough assessment and individualized care. “We take the time to assess whether TRT is the right choice for you,” he states, stressing that Ulo is dedicated to providing ongoing support rather than rushing clients into treatment.
The mission of Ulo is clear: to make the process of testosterone therapy safe, efficient, and transparent. Every aspect of the program is designed to foster long-term health outcomes for men.
In a recent interview, Patel addressed some frequently asked questions regarding Ulo’s TRT program:
What does Ulo’s TRT program include?
“At Ulo, we provide a full-service program that encompasses comprehensive blood work, one-on-one consultations with licensed physicians, prescriptions, custom treatment plans, and regular follow-ups,” Patel explains. This approach minimizes the need for in-person visits.
Who oversees the treatment?
“Every treatment plan at Ulo is supervised by a licensed, U.S.-based physician who specializes in hormone optimization and men’s health,” he states. This ensures individualized medical supervision tailored to the patient’s unique needs.
How is TRT administered?
“Injections are the most reliable method, typically given once or twice a week. While some men prefer gels or creams, these can be less consistent in absorption,” Patel adds. Most men find that self-administration at home is quick and straightforward.
Will TRT affect fertility?
“Yes, it can potentially reduce sperm production. However, there are fertility-preserving medications that can be taken alongside TRT,” he notes, highlighting a study that found over 90% of men maintained normal sperm counts while using these medications.
Is blood work included in the program’s cost?
“Blood work is included, with the first test occurring before the initial consultation. Follow-up tests are conducted every quarter to ensure the treatment remains safe and effective,” Patel confirms.
Ulo’s model provides a flat monthly rate covering physician oversight, medication, lab testing, and access to care teams, thus eliminating unexpected costs. Although most insurance plans do not cover TRT unless testosterone levels are critically low, Ulo operates outside the insurance framework to prioritize patient needs over bureaucratic constraints.
As Ulo continues to evolve, Patel remains committed to fostering a supportive environment for men seeking to reclaim their health through testosterone therapy. The aim is to not only address physical symptoms but also to enhance overall well-being and confidence.
